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PATHOGEN DETECTION

The focus of this consortium is on instant detection and early treatment of harmful organisms. Researchers are developing easy to use, low cost technology for early detection of bacteria present during food preparation such as E.Coli, Listeria, and Salmonella, and in wounds such as Staphylococcus and Streptococcus. Current projects include:

Smart Bandage. Inexpensive, lightweight biosensors for early detection of pathogens capable of causing human infection.

View video about the Smart Bandage project

Biosmart Materials. New packaging materials capable of signaling the presence of contaminating pathogens-such as bacteria-in food or beverages.

Leader:
Benjamin Miller, Ph.D.

Team:
Todd Kraus, Ph.D.
Lewis Rothberg, Ph.D.
Philippe Fauchet, Ph.D.
Thomas Jones, Ph.D.

Publications About Center Research
M. Archer and P. M. Fauchet, "Electrical Sensing Of DNA Hybridization In Porous Silicon Layers," to appear in Phys. Stat. Sol. (2002).

S. Chan, S. R. Horner, P. M. Fauchet, and B. L. Miller, "Identification Of Gram Negative Bacteria Using Nanoscale Silicon Microcavities," J. Am. Chem. Soc. 123, 11797-11798 (2001).

S. Chan, S. R. Horner, B. L. Miller, and P. M. Fauchet, "Nanoscale Silicon Microcavity Optical Sensors For Biological Applications," Mat. Res. Soc. Symp. Proc. 638, F10.4.1-10.4.6 (2001).

S. Chan, P. M. Fauchet, Y. Li, and L. J. Rothberg, "Nanoscale Microcavities For Biomedical Sensor Applications," in Micro- and Nanotechnology for Biomedical and Environmental Applications, edited by R. P. Mariella, Jr. (SPIE, Bellingham, WA, 2000), Vol. 3912, pp 23-34.

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, "Nanoscale Silicon Microcavities For Biosensing," Mat. Sci. & Eng. C15, 277-282 (2001) (Invited).

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, "Porous Silicon Microcavities For Biosensing Applications," Phys. Stat. Sol. (a) 182, 541-546 (2000).

T. B. Jones , "Liquid Dielectrophoresis on the Microscale Dynamics of Dielectrophoretic Liquid Microactuation," Journal of Electrostatics 51-52 (2001) 290-299.

Relevant Publications by Center Researchers
S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, "Nanoscale Silicon Microcavities For Biosensing," Mat. Sci. & Eng. C15, 277-282 (2001) (Invited).

P. M. Fauchet, "Active photonic bandgap structures," invited presentation at 2002 Photonic Nanostructures: Advancing Materials to Control Light, October 24, San Diego

P. M. Fauchet, "Silicon: Porous," in Encyclopedia of Applied Physics, Update 2, Wiley-VCH Verlag, pp. 249-272 (1999)

P. M. Fauchet, "Porous Silicon Based Biosensors," to appear in the Proc. of the Biochips 2002 conference.

 

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